Polarized Zeeman-effect flameless atomic absorption spectrometry of cadmium, copper, lead, and manganese in human kidney cortex

Journal Article · Thu Jan 01 04:00:00 EST 1981 · Clin. Chem.; (United States)

OSTI ID:6935488

Peleban, P A; Kerkay, J; Pearson, K H

Polarized Zeeman-effect flameless atomic absorption spectroscopy was used to quantitatively measure cadmium, copper, lead, and manganese in a nitric acid digest of lyophilized human kidney cortex. Within-run coefficients of variation for cadmium, copper, lead, and manganese were 4.1, 6.3, 3.7, and 5.6%, respectively. Between-run coefficients of variation were 6.9, 5.5, 5.9, and 6.3%, respectively, for cadmium, copper, lead, and manganese. The detection limits were 5.2 ..mu..g/L for copper, 1.2 ..mu..g/L for both cadmium and lead, and 0.8 ..mu..g/L for manganese. Assays were linear to 75 ..mu..g/L for cadmium, 100 ..mu..g/L for manganese, and 200 ..mu..g/L for copper and lead. Average analytical recoveries for the four metals ranged between 95 and 101%. Because these metals were quantitated in the same digest of kidney cortex, the values for each digest gave a trace-metal profile for each autopsy specimen.

• OSTI ID: 6935488
• Journal Information: Clin. Chem.; (United States), Journal Name: Clin. Chem.; (United States) Vol. 27:1; ISSN CLCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400104* -- Spectral Procedures-- (-1987)
560306 -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTROSCOPY
ANIMALS
BODY
CADMIUM
CHEMICAL ANALYSIS
COMPARATIVE EVALUATIONS
COPPER
ELEMENTS
KIDNEYS
LEAD
MAMMALS
MAN
MANGANESE
METALS
ORGANS
PRIMATES
QUANTITATIVE CHEMICAL ANALYSIS
QUANTITY RATIO
SPECTROSCOPY
TRACE AMOUNTS
TRANSITION ELEMENTS
VERTEBRATES