Cadmium in kidney cortex, liver, and pancreas from Swedish autopsies. Estimation of biological half time in kidney cortex, considering calorie intake and smoking habits

Journal Article · Thu Jan 01 04:00:00 EST 1976 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1976.10667239· OSTI ID:7106721

Elinder, C G ^[1]; Kjellstrom, T; Friberg, L; Lind, B; Linnman, L

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1. Karolinska Inst., Stockholm

Cadmium and zinc have been analyzed in tissues from 292 persons autopsied in Stockholm. In kidney cortex, liver, and pancreas the individual cadmium levels are distributed in a lognormal way. In kidney cortex there is a continuous accumulation of cadmium with age up to 50 years, followed by a decrease. Smokers show a higher cadmium accumulation. For nonsmokers, the biological half time of cadmium in kidney cortex is estimated at 30 years, with an average concentration at age 50 of 11 ..mu..g/g wet weight. When smokers are included, the average cadmium concentration at age 50 is 22 ..mu..g/g wet weight. Based on the more pronounced cadmium accumulation among smokers than nonsmokers, the respiratory absorption rate of cadmium from tobacco smoke is estimated to be approximately 50 percent.

• OSTI ID: 7106721
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 31:6; ISSN AEHLA
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AIR POLLUTION
AUTOPSY
BIOLOGICAL ACCUMULATION
BODY
BUILDUP
CADMIUM
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISTRIBUTION
ELEMENTS
ENDOCRINE GLANDS
EUROPE
GLANDS
KIDNEYS
LIVER
METALS
ORGANS
PANCREAS
POLLUTION
SCANDINAVIA
SWEDEN
TISSUE DISTRIBUTION
ZINC