Mediastinal fibrosis simulating residual Hodgkin's disease

Journal Article · · Am. J. Med. Sci.; (United States)

DOI:https://doi.org/10.1097/00000441-198401000-00009· OSTI ID:6916232

Markman, M

A 28-year-old male with nodular sclerosing Hodgkin's disease and massive mediastinal adenopathy was treated with combination chemotherapy and radiotherapy. Following 1,300 rads and six cycles of chemotherapy the patient was felt, on the basis of chest x-ray and CT scan, to have extensive residual mediastinal and intrapericardial involvement with tumor. At thoracotomy he was found to have markedly enlarged mediastinal lymph nodes with the normal tissue being replaced by dense sclerotic material without tumor. In Hodgkin's disease, CT scanning has proved to be an extremely valuable tool in assisting in staging and treatment planning. This case emphasizes, however, that one must be cautious in the interpretation of persistent abnormalities following curative therapy. Carefully selected patient information obtained from exploratory thoracotomy continues to be helpful in defining disease status.

• Research Organization: Department of Medicine, UCSD School of Medicine
• OSTI ID: 6916232
• Journal Information: Am. J. Med. Sci.; (United States), Journal Name: Am. J. Med. Sci.; (United States) Vol. 287:1; ISSN AJMSA
• Country of Publication: United States
• Language: English

Related Subjects

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62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
BODY AREAS
CARDIOVASCULAR SYSTEM
CHEMOTHERAPY
CHEST
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
HEART
HODGKINS DISEASE
LYMPHOMAS
MEDIASTINUM
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
RADIOLOGY
RADIOTHERAPY
THERAPY
TOMOGRAPHY