Thoracic CT scanning for mediastinal Hodgkin's disease: results and therapeutic implications

Journal Article · Sat Oct 01 04:00:00 EDT 1983 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(83)90317-6· OSTI ID:6724650

Rostock, R A; Siegelman, S S; Lenhard, R E; Wharam, M D; Order, S E

Thoracic CT scans were performed on 42 newly diagnosed patients with Hodgkin's disease. Five of 10 patients with negative chest X ray (CXR) had abnormal thoracic CT scans. Among the remaining 32 patients with mediastinal Hodgkin's disease (MHD) on CXR, pericardial (Ep) and chest wall invasion (Ec) were the two most common sites of involvement which were detectable by CT scan alone. Ep and Ec accounted for 16 of 19 of the changes in treatment portal or philosophy based on CT scan findings. Because of the high risk of cardiac or pulmonary radiation toxicity in Ep or Ec, radiation treatment alone may be inadequate. Treatment of mediastinal Hodgkin's disease is reviewed here. The use of CT scans for identification of Ep, Ec, and other abnormalities will allow for more precise treatment, further define the use of conventional radiotherapy, combined modality therapy or whole lung irradiation, and allow more accurate analysis of treatment results.

• Research Organization: John Hopkins Medical Inst., Baltimore, MD
• OSTI ID: 6724650
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 9:10; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

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62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
BODY AREAS
CARDIOVASCULAR SYSTEM
CHEST
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
HEART
HODGKINS DISEASE
LYMPHOMAS
MEDIASTINUM
MEDICINE
MEMBRANES
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PERICARDIUM
PLANNING
RADIOLOGY
RADIOTHERAPY
SEROUS MEMBRANES
THERAPY
TOMOGRAPHY