Comparison of pretinning methods to label leukocytes with technetium-99m

Journal Article · Wed Jun 01 04:00:00 EDT 1988 · J. Nucl. Med. Technol.; (United States)

OSTI ID:6879164

Gerson, B; Ballinger, J R; Reid, R H; Gulenchyn, K Y

Leukocytes labeled with technetium-99m using pretinning with stannous complexes of pyrophosphate, glucoheptonate, and gentisic acid were compared with respect to labeling efficiency, time required for labeling, in vitro cell viability, initial lung transit, and image quality following reinjection into normal volunteers. Gentisic acid pretinning was the best method, offering the shortest preparation time, moderate labeling efficiency, rapid lung clearance, and greatest in vivo stability.

• Research Organization: Ottawa Civic Hospital, Ontario (Canada)
• OSTI ID: 6879164
• Journal Information: J. Nucl. Med. Technol.; (United States), Journal Name: J. Nucl. Med. Technol.; (United States) Vol. 16:2; ISSN JNMTB
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400702 -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOXYLIC ACID ESTERS
CHEMICAL PROPERTIES
COMPLEXES
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DRUGS
ESTERS
GLUCOHEPTONATE
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LEUKOCYTES
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
PATIENTS
PERTECHNETATES
PH VALUE
PHOSPHORUS COMPOUNDS
PYROPHOSPHATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOPHARMACEUTICALS
REFRACTORY METAL COMPOUNDS
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TIN COMPLEXES
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES