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Electron spin resonance imaging and in vivo electron spin resonance studies of biological and non-biological systems

Thesis/Dissertation ·
OSTI ID:6866916
The monitoring of a crack forming during the swelling demonstrated the ability of the ESR imaging technique to examine microscopic diffusion processes. Moreover, the time dependent images of two coal samples demonstrated the feasibility of using ESR imaging in studying coal oxidation processes and at the same time showed the limit of the imaging approach employed in handling broad lineshape functions. An in situ melanoma tumor implanted in the tail of a mouse was also imaged with the aid of nitroxide spin probes. Both potential pathological features and the dynamic processes were investigated. In vivo ESR was used to measure pharmacokinetics of four nitroxides in mice and seven nitroxides in rats. A home made L-band ESR system using a two-arm one-entrance resonator was employed in the research.
Research Organization:
Ohio State Univ., Columbus, OH (USA)
OSTI ID:
6866916
Country of Publication:
United States
Language:
English