Mixture of chemical protective agents used to prevent radiation-induced testicular lesions. [. gamma. rays; mice; DMSO; reduced glutathione; MEA]
Journal Article
·
· Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:6830271
The spermatogenic epithelium is one of the most radiosensitive tissues of the organism. It is known that ionizing radiation inhibits reproduction and development of germ cells, inducing structural and functional disturbances and chromosomal aberrations in them, as well as destruction. The use of radioprotective agents is one possibility for preventing or attenuating the reaction to radiation. The protective agents known for their high efficacy in protecting the body or some vital tissues were found to be considerably less effective with regard to germ cells.
- Research Organization:
- Inst. of Ecology of Plants and Animals, Sverdlovsk, USSR
- OSTI ID:
- 6830271
- Journal Information:
- Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 18:1; ISSN RADBA
- Country of Publication:
- United States
- Language:
- English
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Journal Article
·
Sat Aug 01 00:00:00 EDT 1981
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·
OSTI ID:6314866
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Technical Report
·
Thu Dec 31 23:00:00 EST 1959
· Akademiya Nauk S.S.S.R.
·
OSTI ID:4035137
Sister chromatid exchanges and chromosome aberrations induced by radiosensitizing agents in bone marrow cells of treated tumor-bearing mice
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Related Subjects
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
COBALT 60
COBALT ISOTOPES
DMSO
DRUGS
ELECTROMAGNETIC RADIATION
GAMETES
GAMMA RADIATION
GERM CELLS
GLUTATHIONE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MEA
MICE
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PEPTIDES
POLYPEPTIDES
PROTEINS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
RADIOSENSITIVITY EFFECTS
RESPONSE MODIFYING FACTORS
RODENTS
SPERMATOCYTES
SPERMATOGONIA
SPERMATOZOA
SULFOXIDES
THIOLS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
COBALT 60
COBALT ISOTOPES
DMSO
DRUGS
ELECTROMAGNETIC RADIATION
GAMETES
GAMMA RADIATION
GERM CELLS
GLUTATHIONE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MEA
MICE
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PEPTIDES
POLYPEPTIDES
PROTEINS
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
RADIOSENSITIVITY EFFECTS
RESPONSE MODIFYING FACTORS
RODENTS
SPERMATOCYTES
SPERMATOGONIA
SPERMATOZOA
SULFOXIDES
THIOLS
VERTEBRATES
YEARS LIVING RADIOISOTOPES