Radiosensitivity of hair follicles in mouse dorsum and tail

Journal Article · Wed Oct 01 04:00:00 EDT 1980 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575220· OSTI ID:6817413

Hendry, J H; Edmundson, J M; Potten, C S

The radiosensitivity of murine hair follicles was measured in two skin sites, dorsal body and tail. Follicles were considered viable if they appeared histologically similar to controls 4 or 8 weeks after irradiation or similar to growing follicles 12 days after plucking. Dorsal follicles were either unplucked or plucked after and/or before irradiation. Tail follicles were unplucked, but at the time of irradiation the tails were either in air or clamped to induce severe hypoxia, or the mice were anesthetized. The differences in dorsal follicle sensitivity were compared with other widely varying values reported in the literature. The relative sensitivities of the tail follicles in different conditions at the time of irradiation were similar to previous relative sensitivities measured for tail necrosis.

• Research Organization: Christie Hospital and Holt Radium Inst., Manchester, United Kingdom
• OSTI ID: 6817413
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 84:1; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DATA
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
HAIR FOLLICLES
HISTOLOGY
INFORMATION
IONIZING RADIATIONS
MAMMALS
MICE
NECROSIS
NUMERICAL DATA
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RADIATIONS
RADIOSENSITIVITY
RODENTS
SKIN
SURVIVAL CURVES
VERTEBRATES
X RADIATION