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Effects of some mutations on radiosensitivity of haploid and diploid yeast. [. gamma. rays; Saccharomyces cerevisiae]

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:6788582
;
A series of haploid strains of Saccharomyces cerevisiae yeast is described, which differ by almost 100% in radiosensitivity (D/sub 0/ 5.7 to 10.8 krad). The diploid strains obtained from them by means of self-diploidization and hybridization demonstrated a 5-fold difference in radiosensitivity (D/sub 0/ 9.6 to 50.0 krad). It was established that some mutations (presumably adel-6) can affect the radiosensitivity of haploid and diploid yeasts in opposite directions, i.e., they can lower the radiosensitivity of haploid cells and raise that of diploid cells. It was demonstrated that the effect on radiosensitivity of such mutations is independent of heterozygosity for the mating (pairing) type locus. No correlation was established between the changes in values of D/sub 0/, extrapolation number n, inactivation form ratio, and level of recovery when kept in a non-nutrient medium.
Research Organization:
Scientific Research Inst. of Medical Radiology, Obninsk, USSR
OSTI ID:
6788582
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 18:1; ISSN RADBA
Country of Publication:
United States
Language:
English

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Related Subjects

550400 -- Genetics
560131* -- Radiation Effects on Microorganisms-- Basic Studies-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL VARIABILITY
BIOMASS
COBALT 60
COBALT ISOTOPES
DIPLOIDY
ELECTROMAGNETIC RADIATION
ENERGY SOURCES
FUNGI
GAMMA RADIATION
GENE MUTATIONS
GENETIC VARIABILITY
HAPLOIDY
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MICROORGANISMS
MINUTES LIVING RADIOISOTOPES
MUTATIONS
NUCLEI
ODD-ODD NUCLEI
PLANTS
PLOIDY
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOSENSITIVITY
RADIOSENSITIVITY EFFECTS
RECOVERY
RENEWABLE ENERGY SOURCES
SACCHAROMYCES
SACCHAROMYCES CEREVISIAE
SURVIVAL TIME
YEARS LIVING RADIOISOTOPES
YEASTS