Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Radiosensitivity and sulfhydryl group content of yeast of different genotypes. [Saccharomyces cerevisiae, gamma radiation]

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:6788552
A study was made of radiosensitivity and sulfhydryl group content of haploid and diploid Saccharomyces cerevisiae yeast of the ''wild type'' with the rad 54 mutation. It was established that, in ''wild type'' yeast, cells in the logarithmic phase of growth are not only more radioresistant than cells in the stationary phase of growth, but they contain more SH groups. In yeast carrying the rad 54 mutation, cells in the logarithmic phase of growth differ little from those in the stationary phase, with regard to both radioresistance and SH group content. No substantial differences were demonstrated in SH group content of haploid and diploid cells of different genotypes at the stationary phase of growth. The hypothesis is expounded that the influence of the rad 54 mutation on differences in radiosensitivity of yeast in different growth phases may be related to the disturbances in regulation of SH compound synthesis induced by this mutation.
Research Organization:
All-Union Scientific Research Inst. of Genetics and Breeding of Industrial Microorganisms, Moscow
OSTI ID:
6788552
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:6; ISSN RADBA
Country of Publication:
United States
Language:
English