Precursors to radiopharmaceutical agents for tissue imaging
Patent
·
OSTI ID:6757622
A compound is described comprising: a heterocyclic moiety wherein the hetero member of the heterocyclic moiety is nitrogen; the heterocyclic moiety being quaternary and capable of being reduced to a dihydrogenated form; the heterocyclic moiety having a carbonyl group attached to a carbon of the ring of the heterocyclic moiety; the heterocyclic moiety being coupled at the carbonyl carbon with the amino nitrogen of an aromatic or aromatic alkyl amine; the aromatic or aromatic alkyl amine having attached to a carbon of the aromatic ring a moiety that is readily replaced by a radiohalide selected from the group a substituted triazene, mercuric acetate and a boron moiety.
- Assignee:
- Dept. of Energy, Washington, DC
- Patent Number(s):
- US 4764598
- OSTI ID:
- 6757622
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ACETATES
ALKYL RADICALS
AMINES
ANIMAL TISSUES
AROMATICS
AZINES
BODY
BORON
CARBOXYLIC ACID SALTS
CHEMICAL COMPOSITION
DIAGNOSTIC USES
DRUGS
ELEMENTS
HALIDES
HALOGEN COMPOUNDS
HETEROCYCLIC COMPOUNDS
IMAGE PROCESSING
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MEDICINE
MERCURY COMPOUNDS
NITROGEN COMPOUNDS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PROCESSING
RADICALS
RADIOPHARMACEUTICALS
SEMIMETALS
TISSUES
TRACER TECHNIQUES
TRIAZINES
USES
62 RADIOLOGY AND NUCLEAR MEDICINE
ACETATES
ALKYL RADICALS
AMINES
ANIMAL TISSUES
AROMATICS
AZINES
BODY
BORON
CARBOXYLIC ACID SALTS
CHEMICAL COMPOSITION
DIAGNOSTIC USES
DRUGS
ELEMENTS
HALIDES
HALOGEN COMPOUNDS
HETEROCYCLIC COMPOUNDS
IMAGE PROCESSING
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MEDICINE
MERCURY COMPOUNDS
NITROGEN COMPOUNDS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PROCESSING
RADICALS
RADIOPHARMACEUTICALS
SEMIMETALS
TISSUES
TRACER TECHNIQUES
TRIAZINES
USES