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Effect of Manganese on some aspects of carbohydrate metabolism in rats. [None]

Journal Article · · Bull. Environ. Contam. Toxicol.; (United States)
DOI:https://doi.org/10.1007/BF01985585· OSTI ID:6737619
; ;
Numerous biochemical and toxicological studies have indicated that chronic exposure to manganese leads to neurological abnormalities. Increasing use of manganese compounds as antiknocks in gasoline and diesel fuel has aroused a great concern over the toxicological potential of this metal and stressed the need for understanding the mechanism of its poisoning. Reports of alerations in the levels of biogenic amines have helped in understanding the basis of neurological disorders. However, little is known about the mechanism by which manganese exposure leads to hypoglycemia in workers. This study deals with the influence of manganese exposure on metabolism of glucose, the chief fuel of the brain, and some enzymes involved in its oxidation. These studies will provide an assessment of the extent to which manganese affects the various processes controlling carbohydrate metabolism.
Research Organization:
Industrial Toxicology Research Center, Lucknow, India
OSTI ID:
6737619
Journal Information:
Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 25:4; ISSN BECTA
Country of Publication:
United States
Language:
English

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Related Subjects

550200 -- Biochemistry
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALDEHYDES
ANIMALS
BIOASSAY
BIOCHEMICAL REACTION KINETICS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BODY
BODY FLUIDS
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
CHEMICAL ANALYSIS
CHEMICAL REACTIONS
DIGESTIVE SYSTEM
ELEMENTS
ENZYME ACTIVITY
GLANDS
GLUCOSE
GLYCOGEN
HEXOSES
HYPERGLYCEMIA
KINETICS
LIVER
MAMMALS
MANGANESE
MATERIALS
METABOLISM
METALS
MONOSACCHARIDES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
OXIDATION
POLYSACCHARIDES
QUANTITATIVE CHEMICAL ANALYSIS
RATS
REACTION KINETICS
RODENTS
SACCHARIDES
TIME DEPENDENCE
TOXICITY
TRANSITION ELEMENTS
VERTEBRATES