Preliminary assessment of the relative toxicity of 1,5-diazido-3-nitrazapentane 90-day dermal application male and female rabbits study number 75-51-y809-90, May 1990 - June 1992. Phase 2. Final report, May 1990-June 1992
Technical Report
·
OSTI ID:6712236
A 90-day application of DANPE has the potential to cause testicular hypospermatogenesis in male rabbits and an apparent inhibition of mature ovarian follicles formation in female rabbits. A no-observed-adverse-effect-level was not achieved in the male rabbits but was achieved in female rabbits at 27.3 mg/kg dose level.... 1,5-Diazido-3-Nitrazapentane, Dermal, Approximate Lethal Dose (ALD), Testicular hypospermatogenesis, Ovarian follicle No-observed-adverse-effect-level (NOAEL).
- Research Organization:
- Army Environmental Hygiene Agency, Aberdeen Proving Ground, MD (United States)
- OSTI ID:
- 6712236
- Report Number(s):
- AD-A-259309/3/XAB; USAEHA--75-51-0809-92
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKANES
ANIMALS
BODY
DOSE-RESPONSE RELATIONSHIPS
HORMONES
HYDROCARBONS
INHIBITION
MAMMALS
ORGANIC COMPOUNDS
ORGANS
PENTANE
RABBITS
SEX
SEX DEPENDENCE
SKIN
TOXICITY
USES
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKANES
ANIMALS
BODY
DOSE-RESPONSE RELATIONSHIPS
HORMONES
HYDROCARBONS
INHIBITION
MAMMALS
ORGANIC COMPOUNDS
ORGANS
PENTANE
RABBITS
SEX
SEX DEPENDENCE
SKIN
TOXICITY
USES
VERTEBRATES