Work in progress: (/sup 18/F) fluorodeoxyglucose and positron emission tomogrphy in the evaluation of radiation necrosis of the brain

Journal Article · Wed Sep 01 00:00:00 EDT 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.144.4.6981123· OSTI ID:6710150

Patronas, N J ^[1]; Di Chiro, G; Brooks, R A

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1. National Inst. of Neurological and Communicative Disorders and Stroke, Bethesda, MD

Five patients who had undergone radiation therapy for cerebral tumors and whose conditions were deteriorating were examined by means of positron emission tomography (PET) with (/sup 18/F) fluorodeoxyglucose. All five cases had similar clinical and computed tomographic findings. Using the PET technique the two cases of radiation necrosis were distinguished from the three recurrent tumors. In the two cases of radiation necrosis the rate of glucose utilization in the lesion was markedly reduced compared with the normal brain parenchyma. In the recurrent gliomas, however, the glucose metabolic rate was evaluated. All five diagnoses were confirmed by biopsy or autopsy.

• OSTI ID: 6710150
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 144:4; ISSN RADLA
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALDEHYDES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
EMISSION COMPUTED TOMOGRAPHY
FLUORINE 18
FLUORINE ISOTOPES
GLUCOSE
HEXOSES
HOURS LIVING RADIOISOTOPES
ISOTOPES
LIGHT NUCLEI
MEDICINE
MONOSACCHARIDES
NECROSIS
NEOPLASMS
NERVOUS SYSTEM
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
POSITRON COMPUTED TOMOGRAPHY
RADIATION EFFECTS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SACCHARIDES
SIDE EFFECTS
THERAPY
TOMOGRAPHY