Small hepatocellular carcinomas in chronic liver disease: Detection with SPECT
Single-photon emission computed tomography (SPECT) performed using a rotating gamma camera was compared with ..cap alpha../sub 1/-fetoprotein (AFP) assay, conventional liver scintigraphy, ultrasound (US) imaging, computed tomography (CT), and selective celiac angiography in 40 patients with a total of 50 small hepatocellular carcinomas (HCCs;<5 cm). The detection rates of US and CT were determined on an initial screening study and on a second, more precisely focused study. The detection rate of small HCCs by the various modalities was as follows: AFP, 13%; liver scintigraphy, 36%; SPECT, 72%; initial screening US, 80%; second, more precise US studies, 94%; initial screening CT, 64%; second, more precise CT study, 82%; angiography, 88%. Although SPECT was inferior to the initial screening US examination in detecting HCCs less than 2 cm in size, its sensitivity was identical to that of the initial screening US study for detecting HCCs of 2-5 cm. The combination of SPECT and US was an excellent method for the early detection of HCCs, yielding a detection rate of 94%.
- Research Organization:
- Kobe General Hospital, 4-6, Minatojima-Nakamachi, Chuo-Ku Kobe 650
- OSTI ID:
- 6699980
- Report Number(s):
- CONF-861136-; TRN: 87-013261
- Journal Information:
- Radiology; (United States), Vol. 159:3; Conference: 72. scientific assembly and annual meeting of RSNA, Chicago, IL, USA, 30 Nov 1986
- Country of Publication:
- United States
- Language:
- English
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GAMMA CAMERAS
ULTRASONOGRAPHY
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550602* - Medicine- External Radiation in Diagnostics- (1980-)