Diagnosis and screening of small hepatocellular carcinomas. Comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and alpha 1-fetoprotein assay

Journal Article · Wed Dec 01 00:00:00 EST 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.145.3.6183708· OSTI ID:6186372

Takashima, T; Matsui, O; Suzuki, M; Ida, M

Twenty-nine small (less than 5 cm) hepatocellular carcinomas in 18 patients were examined by radionuclide imaging (RN), ultrasound (US), computed tomography (CT), hepatic angiography, and serum alpha 1-fetoprotein (AFP) assay. Sensitivity was 39% with RN, 50% with US, 56% with CT, and 94% with angiography, including infusion hepatic angiography (IHA). Lesions larger than 3 cm could be detected by all of these methods; those between 2 and 3 cm were generally shown by US and CT but not RN. IHA was essential for diagnosis of lesions less than 2 cm, which were otherwise difficult or impossible to detect except with angiography. As a screening method, AFP was best, followed by US and CT. The authors recommend using AFP and US to minimize expense and radiation exposure. In questionable cases, IHA should be performed.

• Research Organization: Department of Radiology, Kanazawa University School of Medicine, Japan
• OSTI ID: 6186372
• Journal Information: Radiology; (United States), Vol. 145:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
CARCINOMAS
DIAGNOSIS
LIVER
COMPUTERIZED TOMOGRAPHY
RADIOISOTOPE SCANNING
ULTRASONOGRAPHY
BIOASSAY
COMPARATIVE EVALUATIONS
DIAGNOSTIC USES
LIVER CELLS
PATIENTS
ANIMAL CELLS
BODY
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
GLANDS
NEOPLASMS
ORGANS
SOMATIC CELLS
TOMOGRAPHY
USES
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