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Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay

Journal Article · · Radiology; (United States)
; ; ;

Twenty-nine small (<5 cm) hepatocellular carcinomas in 18 patients were examined by radionuclide imaging (RN), ultrasound (US), computed tomography (CT), hepatic angiography, and serum ..cap alpha../sub 1/-fetoprotein (AFP) assay. Sensitivity was 39% with RN, 50% with US, 56% with CT, and 94% with angiography, including infusion hepatic angiography (IHA). Lesions larger than 3 cm could be detected by all of these methods; those between 2 and 3 cm were generally shown by US and CT but not RN. IHA was essential for diagnosis of lesions less than 2 cm, which were otherwise difficult or impossible to detect except with angiography. As a screening method, AFP was best, followed by US and CT. The authors recommend using AFP and US to minimize expense and radiation exposure. In questionable cases, IHA should be performed.

Research Organization:
Kanazawa Univ. School of Medicine, Japan
OSTI ID:
6172929
Journal Information:
Radiology; (United States), Journal Name: Radiology; (United States) Vol. 145:3; ISSN RADLA
Country of Publication:
United States
Language:
English

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62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOASSAY
BIOMEDICAL RADIOGRAPHY
BODY
CARCINOMAS
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COMPARATIVE EVALUATIONS
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DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
DISPERSIONS
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIVER
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PROTEINS
RADIOCOLLOIDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
TOMOGRAPHY
ULTRASONOGRAPHY
YEARS LIVING RADIOISOTOPES