Diagnosis and screening of small hepatocellular carcinomas: comparison of radionuclide imaging, ultrasound, computed tomography, hepatic angiography, and. cap alpha. /sub 1/-fetoprotein assay

Journal Article · Wed Dec 01 00:00:00 EST 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.145.3.6183708· OSTI ID:6172929

Takashima, T; Matsui, O; Suzuki, M; Ida, M

Twenty-nine small (<5 cm) hepatocellular carcinomas in 18 patients were examined by radionuclide imaging (RN), ultrasound (US), computed tomography (CT), hepatic angiography, and serum ..cap alpha../sub 1/-fetoprotein (AFP) assay. Sensitivity was 39% with RN, 50% with US, 56% with CT, and 94% with angiography, including infusion hepatic angiography (IHA). Lesions larger than 3 cm could be detected by all of these methods; those between 2 and 3 cm were generally shown by US and CT but not RN. IHA was essential for diagnosis of lesions less than 2 cm, which were otherwise difficult or impossible to detect except with angiography. As a screening method, AFP was best, followed by US and CT. The authors recommend using AFP and US to minimize expense and radiation exposure. In questionable cases, IHA should be performed.

• Research Organization: Kanazawa Univ. School of Medicine, Japan
• OSTI ID: 6172929
• Journal Information: Radiology; (United States), Vol. 145:3
• Country of Publication: United States
• Language: English

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