Stationary phase interactions in supercritical fluid chromatography

Conference · Fri Jul 01 00:00:00 EDT 1988

OSTI ID:6626499

Yonker, C R; Smith, R D

Solute and solvent interactions with the stationary phase are described. A simple thermodynamic model describing retention in supercritical fluid chromatography (SFC) is used to determine the partial molar volume of the solute in the stationary phase at infinite dilution. Adsorption isotherms for 2-propanol on SE-54 as a function of density, temperature, and mole fraction of 2-propanol were studied for the binary fluid system of 2-propanol/CO/sub 2/ using SFC-mass spectrometry (MS). The amount of 2-propanol co-solvent sorbed in the stationary phase decreased with increasing pressure of the binary fluid mobile phase. 8 refs., 4 figs., 1 tab.

• Research Organization: Pacific Northwest Lab., Richland, WA (USA)
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 6626499
• Report Number(s): PNL-SA-15281; CONF-8810218-1; ON: DE89002000
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
ADSORPTION ISOTHERMS
ALCOHOLS
AROMATICS
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CHALCOGENIDES
CHROMATOGRAPHY
CONDENSED AROMATICS
HYDROCARBONS
HYDROXY COMPOUNDS
ISOTHERMS
MATHEMATICAL MODELS
NAPHTHALENE
ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PHASE STUDIES
PROPANOLS
SEPARATION PROCESSES
SOLUTES
SUPERCRITICAL FLUID CHROMATOGRAPHY