Effects of pressure on retention in supercritical fluid chromatography

Journal Article · Thu Jun 04 00:00:00 EDT 1987 · J. Phys. Chem.; (United States)

DOI:https://doi.org/10.1021/j100296a045· OSTI ID:6426012

Yonker, C R; Gale, R W; Smith, R D

A simple thermodynamic relationship is described relating solute retention, pressure, and density for supercritical fluid chromatography (SFC). Solute retention in SFC has been predicted based upon the partial molar volume of the solute in the mobile phase and the polymeric stationary phase at infinite dilution. Calculated chromatographic retention for naphthalene and biphenyl has been compared to experimental data for capillary SFC. Predictions of the thermodynamic model accurately fit the retention data, leading to further insight into the retention mechanism in SFC.

• Research Organization: Pacific Northwest Lab., Richland, WA
• DOE Contract Number: AC06-76RL01830
• OSTI ID: 6426012
• Journal Information: J. Phys. Chem.; (United States), Journal Name: J. Phys. Chem.; (United States) Vol. 91:12; ISSN JPCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
AROMATICS
BIPHENYL
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CHALCOGENIDES
CHROMATOGRAPHY
CONDENSED AROMATICS
DATA
DENSITY
EXPERIMENTAL DATA
HYDROCARBONS
INFORMATION
MEDIUM TEMPERATURE
NAPHTHALENE
NUMERICAL DATA
ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PERFORMANCE
PHYSICAL PROPERTIES
PRESSURE DEPENDENCE
QUANTITY RATIO
REMOVAL
SEPARATION PROCESSES
SOLUTES
SUPERCRITICAL FLUID CHROMATOGRAPHY
THERMODYNAMIC PROPERTIES
THERMODYNAMICS