Cutaneous manifestations of tetrachlorodibenzo-p-dioxin in children and adolescents. Follow-up 10 years after the Seveso, Italy, accident

Journal Article · Tue Nov 01 00:00:00 EST 1988 · J. Am. Acad. Dermatol.; (United States)

DOI:https://doi.org/10.1016/S0190-9622(88)70238-8· OSTI ID:6608246

Caputo, R; Monti, M; Ermacora, E; Carminati, G; Gelmetti, C; Gianotti, R; Gianni, E; Puccinelli, V

After an accident in a chemical plant in Seveso, Italy, on July 10, 1976, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) spread over a populated area. The event was exceptional because children were also affected and because the contamination took place not only through direct exposure but also through inhalation and the ingestion of contaminated foods, especially fruits and vegetables. This paper illustrates the early dermatologic lesions, the late acneic (chloracne) lesions, and their evolution during a 10-year period. Peculiar cutaneous findings, histologic data, and a comparison with previously reported similar accidents are also included.

• Research Organization: Univ. of Milan (Italy)
• OSTI ID: 6608246
• Journal Information: J. Am. Acad. Dermatol.; (United States), Vol. 19
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
DIOXIN
TOXICITY
SKIN
SENSITIVITY
SKIN DISEASES
EPIDEMIOLOGY
ADOLESCENTS
CHILDREN
ERYTHEMA
ITALY
AGE GROUPS
BODY
DISEASES
EUROPE
HETEROCYCLIC COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
SYMPTOMS
WESTERN EUROPE
560300* - Chemicals Metabolism & Toxicology
550900 - Pathology