Cutaneous manifestations of tetrachlorodibenzo-p-dioxin in children and adolescents. Follow-up 10 years after the Seveso, Italy, accident

Journal Article · Tue Nov 01 04:00:00 EST 1988 · J. Am. Acad. Dermatol.; (United States)

DOI:https://doi.org/10.1016/S0190-9622(88)70238-8· OSTI ID:6608246

Caputo, R; Monti, M; Ermacora, E; Carminati, G; Gelmetti, C; Gianotti, R; Gianni, E; Puccinelli, V

After an accident in a chemical plant in Seveso, Italy, on July 10, 1976, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) spread over a populated area. The event was exceptional because children were also affected and because the contamination took place not only through direct exposure but also through inhalation and the ingestion of contaminated foods, especially fruits and vegetables. This paper illustrates the early dermatologic lesions, the late acneic (chloracne) lesions, and their evolution during a 10-year period. Peculiar cutaneous findings, histologic data, and a comparison with previously reported similar accidents are also included.

• Research Organization: Univ. of Milan (Italy)
• OSTI ID: 6608246
• Journal Information: J. Am. Acad. Dermatol.; (United States), Journal Name: J. Am. Acad. Dermatol.; (United States) Vol. 19; ISSN JAADD
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADOLESCENTS
AGE GROUPS
BODY
CHILDREN
DIOXIN
DISEASES
EPIDEMIOLOGY
ERYTHEMA
EUROPE
HETEROCYCLIC COMPOUNDS
ITALY
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
SENSITIVITY
SKIN
SKIN DISEASES
SYMPTOMS
TOXICITY
WESTERN EUROPE