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Zinc-binding proteins detected by protein blotting

Journal Article · · Anal. Biochem.; (United States)

The Western blotting technique was used for the detection of zinc-binding proteins. Proteins were separated electrophoretically on 15% polyacrylamide-sodium dodecyl sulfate minigels, the gels were soaked in a reduction buffer, and the proteins were transferred to nitrocellulose filters. Zinc-binding proteins were probed with radioactive zinc (/sup 65/Zn) and were detected by autoradiography. This technique allows the detection of as little as 20 to 100 pmol of zinc metalloproteins.

Research Organization:
Institut de Biologie Moleculaire et Cellulaire du CNRS, Strasbourg (France)
OSTI ID:
6602942
Journal Information:
Anal. Biochem.; (United States), Journal Name: Anal. Biochem.; (United States) Vol. 172:1; ISSN ANBCA
Country of Publication:
United States
Language:
English