Relationship between blood and urine concentrations of intact human chorionic gonadotropin and its free subunits in early pregnancy

Journal Article · Wed Apr 01 04:00:00 EST 1987 · Obstet. Gynecol.; (United States)

OSTI ID:6596188

Norman, R J; Menabawey, M; Lowings, C; Buck, R H; Chard, T

Paired blood and urine samples were obtained from patients between the sixth and 14th weeks of normal pregnancy. The levels of intact human chorionic gonadotropin (hCG), and of the free alpha and beta subunits, were measured by specific radioimmunoassays. There was a close association between blood and urine levels of intact hCG and of the alpha subunit of hCG, but no relation between the levels of beta subunit in these sites. These findings suggest that the use of beta subunit assays may give discrepant results according to the fluid examined. By contrast, measurement of intact hCG appears to give similar results in blood and urine.

• Research Organization: St. Bartholomew's Hospital Medical College, London, England
• OSTI ID: 6596188
• Journal Information: Obstet. Gynecol.; (United States), Journal Name: Obstet. Gynecol.; (United States) Vol. 4; ISSN OBGNA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL MATERIALS
BIOLOGICAL WASTES
BLOOD
BODY FLUIDS
GONADOTROPINS
HORMONES
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
MATERIALS
PATIENTS
PEPTIDE HORMONES
PITUITARY HORMONES
PREGNANCY
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNOLOGY
TRACER TECHNIQUES
URINE
WASTES