Chromosome aberrations induced in patients treated with telecobalt therapy for mammary carcinoma

Journal Article · Wed Apr 01 04:00:00 EST 1981 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575608· OSTI ID:6566387

Antoine, J L ^[1]; Gerber, G B; Leonard, A; Richard, F; Wambersie, A

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1. CEN/SCK, Mol, Belgium

The yields of dicentric and ring chromosomes were recorded during telecobalt therapy for mammary carcinoma. The data were fitted to a power or a quadratic function and were compared with those obtained in patients treated for ankylosing spondylitis and nuclear dockyard workers as well as with the results of an in vitro blood irradiation. As expected, the aberration yield for the same absorbed dose level is much greater after irradiation of ankylosing spondylitis than after irradiation for mammary carcinoma; lymphocytes exposed in vitro display the highest rate of aberration. A deviation of the aberrations observed in cells of the mammary carcinoma patients from the theoretical Poisson distribution also indicates that not all lymphocytes in the body has been exposed under these conditions.

• OSTI ID: 6566387
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 86:1; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CARCINOMAS
CHROMOSOMAL ABERRATIONS
COBALT 60
COBALT ISOTOPES
COMPARATIVE EVALUATIONS
CONNECTIVE TISSUE CELLS
DISEASES
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
GLANDS
IN VITRO
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEUKOCYTES
LYMPHOCYTES
MAMMARY GLANDS
MATERIALS
MEDICINE
MINUTES LIVING RADIOISOTOPES
MUTATIONS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATIENTS
PERSONNEL
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RHEUMATIC DISEASES
SIDE EFFECTS
SKELETAL DISEASES
SOMATIC CELLS
SPONDYLITIS
THERAPY
YEARS LIVING RADIOISOTOPES