Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

The relationship of coronary flow reserve (CFR) to stress thallium-201 myocardial perfusion (T1) and radionuclide ventriculography (RNV)

Conference · · J. Nucl. Med.; (United States)
OSTI ID:6548369
; ; ;

Coronary arteriography (CA) can be used to delineate the abnormal anatomy in coronary artery disease (CAD), but the degree of the impairment of coronary blood flow (CBF) cannot be predicted precisely by CA. As a reduction in maximal hyperemic blood flow (MHBF) characterizes a functionally significant coronary lesion, the ratio of contrast-induced MHBF to basal CBF: the coronary flow reserve (CFR) reflects the physiologic significance of a coronary lesion. Recent developments in digital coronary angiography allow CFR to be measured at CA. To assess the relationship of CFR to other noninvasive tests of myocardial perfusion and function the results of stress T1 and RNV were compared to those of CA and CFR for the distribution of 48 arteries in 20 patients. Seven patients had normal CA without spasm: 3 with abnormal CFR had a discrete T1 defect or global RNV dysfunction. The remaining 4 had normal CFR, T1 and RNV. Thirteen had CAD without prior infarction. Segmental T1 and RNV were compared to CA and CFR. Normal CFR was seen in patients with both normal T1 and RNV; while T1 was best associated with abnormal CFR in CAD and may be the preferable noninvasive modality to identify physiologically significant, abnormal CBF in suspected cases of CAD.

Research Organization:
VA Medical Center, Ann Arbor, MI 48105
OSTI ID:
6548369
Report Number(s):
CONF-840619-
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:5; ISSN JNMEA
Country of Publication:
United States
Language:
English

Similar Records

Comparison of the angiographic and scintigraphic evaluation of the success of percutaneous transluminal coronary angioplasty
Conference · Sat Dec 31 23:00:00 EST 1983 · J. Nucl. Med.; (United States) · OSTI ID:6405609
Importance of adequate exercise in the detection of coronary heart disease by radionuclide ventriculography
Journal Article · Sun Nov 30 23:00:00 EST 1980 · J. Nucl. Med.; (United States) · OSTI ID:6689095
Atrial pacing as an alternative to supine exercise (SE) in radionuclide ventriculography (RNV)
Conference · Sat Dec 31 23:00:00 EST 1983 · J. Nucl. Med.; (United States) · OSTI ID:6593696

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BIOMEDICAL RADIOGRAPHY
BLOOD FLOW
BLOOD VESSELS
BODY
CARDIOGRAPHY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
CORONARIES
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DYNAMIC FUNCTION STUDIES
HEART
MEDICINE
MUSCLES
MYOCARDIUM
NUCLEAR MEDICINE
ORGANS
PERFORMANCE
RADIOCARDIOGRAPHY
RADIOISOTOPE SCANNING
RADIOLOGY
RADIONUCLIDE KINETICS
SCINTISCANNING