Atrial pacing as an alternative to supine exercise (SE) in radionuclide ventriculography (RNV)
Stress RNV is at times of limited value as many patients cannot achieve a sufficient pressure rate product (PRP). Atrial pacing is a noninvasive alternative to SE by bicycle ergometry. A swallowable electrode attached to a flexible wire is positioned in a retroatrial position in the esophagus and when connected to a variable output stimulator, variable rate (120, 140, 160 beats/min) atrial pacing ventriculography (APV) can be performed. RNV is performed in the sitting position at rest and at each pacing stage. APV was compared to SE RNV in 4 patients with coronary artery disease (CAD) and 3 normal volunteers (N). Tolerance to APV was excellent with adequate pacing. All subjects reported a minor sensation of chest burning. No arrhythmias occurred. At maximal APV mean PRP was 174 +- 26. The diastolic volumes in APV fell in all patients. Systolic volumes fell in N but not in CAD to APV. A flat EF response to APV was seen in both N and CAD patients. APV is an alternative to SE RNV although PRP remains low. Volume changes in APV are different than in SE RNV and in the interpretation of the results of APV in CAD, changes in systolic and diastolic volumes may be more important than the response of EF.
- Research Organization:
- Univ. of Michigan, Ann Arbor, MI 48105
- OSTI ID:
- 6593696
- Report Number(s):
- CONF-840619-
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:5; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
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551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BIOLOGICAL STRESS
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
BODY
CARDIOGRAPHY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
CORONARIES
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
DRUGS
DYNAMIC FUNCTION STUDIES
ELECTRODES
ESOPHAGUS
EXERCISE
HEART
LABELLED COMPOUNDS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIOCARDIOGRAPHY
RADIOISOTOPE SCANNING
RADIOLOGY
RADIONUCLIDE KINETICS
RADIOPHARMACEUTICALS
SCINTISCANNING