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Comparison of the angiographic and scintigraphic evaluation of the success of percutaneous transluminal coronary angioplasty

Conference · · J. Nucl. Med.; (United States)
OSTI ID:6405609
; ; ; ; ;

The hemodynamic effects of percutaneous transluminal coronary angioplasty (PTCA) are difficult to assess as the change in the degree of arterial stenosis (AS) or transluminal pressure gradients (TPG) do not portray the functional result of this procedure. Diminished maximal hyperemic blood flow (MHBF) characterizes a functionally significant coronary lesion and the ratio of MHBF to basal coronary blood flow: the coronary flow reserve (CFR), which now can be estimated at the time of coronary angiography (CA), is an alternative approach to determining the physiologic significance of a lesion. CFR was obtained in 5 patients with single vessel coronary artery disease (CAD) and compared to stress Thallium-201 myocardial scintigraphy (T1), ejection fraction (EF) and ventricular wall motion (WM) by radionuclide ventriculography (RNV) and the results of CA (AS and TPG) before and after PTCA. Despite the persistence of moderate AS and/or a TPG, T1 and WM returned to normal when CFR was normalized. Thus, T1 and RNV are reliable, noninvasive indicators of the functional results of PTCA and can be used to assess its hemodynamic effects.

Research Organization:
Univ. of Michigan, Ann Arbor, MI 48105
OSTI ID:
6405609
Report Number(s):
CONF-840619-
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:5; ISSN JNMEA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ARTERIES
BIOMEDICAL RADIOGRAPHY
BLOOD CIRCULATION
BLOOD FLOW
BLOOD VESSELS
BODY
CARDIOGRAPHY
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
CORONARIES
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DYNAMIC FUNCTION STUDIES
HEART
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIOCARDIOGRAPHY
RADIOISOTOPE SCANNING
RADIOLOGY
SCINTISCANNING