Effects in rats and guinea pigs of six-month exposures to sulfuric acid mist, ozone, and their combination

Journal Article · Fri Sep 01 04:00:00 EDT 1978 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287397809529705· OSTI ID:6539549

Cavender, F L; Singh, B; Cockrell, B Y

Rats and guinea pigs were exposed to 0.5 ppM O/sub 3/, 10 mg/m/sup 3/ sulfuric acid (H/sub 2/SO/sub 4/) mist, or their combination for 6 h/d, 5 d/wk for 6 mo. Microscopic alterations were seen in the lungs of guinea pigs exposed to O/sub 3/ alone or in combination with H/sub 2/SO/sub 4/ mist. No other microscopic lesions were present in either rats or guinea pigs. No biologically meaningful synergistic effects were noted in animals exposed to the combination of O/sub 3/ and H/sub 2/SO/sub 4/ mist.

• OSTI ID: 6539549
• Journal Information: J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 4:5-6; ISSN JTEHD
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ANIMALS
BIOLOGICAL EFFECTS
CHRONIC EXPOSURE
COLLOIDS
DISEASES
DISPERSIONS
EXPOSURE CHAMBERS
GUINEA PIGS
HYDROGEN COMPOUNDS
INHALATION
INORGANIC ACIDS
INTAKE
MAMMALS
MIXTURES
OZONE
PATHOLOGICAL CHANGES
RATS
RESPIRATORY SYSTEM
RODENTS
SOLS
SULFURIC ACID
TOXICITY
VERTEBRATES