Liver scintigraphy in colon carcinoma: correlation with modified Duke pathological classification

Journal Article · Mon Nov 01 04:00:00 EST 1982 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.145.2.7134452· OSTI ID:6529296

Tanasescu, D E; Waxman, A D; Drickman, M V; Brachman, M B; Ramanna, L; Berman, D S; Waisman, J

Hepatic scintigraphy was performed prior to surgical exploration in 89 patients with primary carcinoma of the large bowel. Of these patients, 26% had positive liver scans at the time the diagnosis was established. The presence or absence of liver metastasis by scintigraphic criteria was correlated with surgical findings, a modified Duke pathologic classification, and the presence of tumor markers. The sensitivity of hepatic scintigraphy was 96% and the specificity was 98%. A total of 63% of patients with abdominal lymph node involvement had positive liver scans while 4.6% of patients without lymph node involvement had positive scans. A total of 91% of patients with positive liver scans had positive abdominal nodes. Of 60 patients with normal liver scans, one (1.7%) had hepatic metastasis and 27% had tumor in regional lymph nodes. Hepatic scintigraphy is highly sensitive in detecting liver metastasis from large bowel carcinoma. However, a negative liver scan did not exclude abdominal lymph node spread.

• Research Organization: Cedars-Sinai Medical Center, Los Angeles, CA
• OSTI ID: 6529296
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 145:2; ISSN RADLA
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
CARCINOMAS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DIGESTIVE SYSTEM
DISEASES
DRUGS
GASTROINTESTINAL TRACT
GLANDS
INTESTINES
LABELLED COMPOUNDS
LARGE INTESTINE
LIVER
LYMPH NODES
LYMPHATIC SYSTEM
MEDICINE
METASTASES
NEOPLASMS
ORGANS
PATHOLOGY
PATIENTS
RADIOISOTOPE SCANNING
RADIOPHARMACEUTICALS
SCINTISCANNING
SURGERY
USES