Evaluation of radionuclide scintigraphy, echography, and serum thyroglobulin in the diagnosis of thyroid nodules

Conference · Sun Jan 01 04:00:00 EST 1984 · J. Nucl. Med.; (United States)

OSTI ID:6932001

Ikekubo, K; Tochio, H; Hamasaki, T; Yamaguchi, H; Saiki, Y; Ito, H; Higa, T; Hirasa, M; Kudo, M; Ishihara, T

For the purpose of rapid and precise diagnosis of thyroid nodules, thyroid imagings with both Tc-99m and Tl-201 were performed in 152 untreated patients with thyroid nodules. Among them, 86 patients were evaluated by ultrasound study. Serum thyroglobulin (Tg) levels were also determined in 69 patients. The final diagnosis of nodules was confirmed by the histological findings. Of the 152 patients, 81 patients (53%) had carcinoma. Scintigraphic patterns obtained with Tc-99m, and Tl-201 were classified into eight types (I-VIII). Abnormal thyroid images were found in 90% of 152 patients. Tl-201 images clearly revealed enormous intrathoracic tumor invasion in 6 carcinomas and 2 adenomas. Of 29 patients with regional lymph-node metastases, 69% showed positive scans with Tl-201 at these sites. The presence and extent of lesions were diagnosed in 99% of 86 patients with scintiscans and ultrasonography. Serum Tg was elevated in 71%. However, there was no significant relationship between Tg levels and scintigraphic patterns. The authors conclude that radionuclide scintigraphy in combination with echography provides improved sensitivity and specificity in detecting the presence and extent of tumor lesions, and is a convenient and useful screening method for the diagnosis of thyroid tumors.

• Research Organization: N. Waseda. Kobe General Hospital, Kobe
• OSTI ID: 6932001
• Report Number(s): CONF-840619-
• Conference Information: Journal Name: J. Nucl. Med.; (United States) Journal Volume: 25:5
• Country of Publication: United States
• Language: English

Related Subjects

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62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARCINOMAS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE GLANDS
GLANDS
GLOBULINS
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
IMAGE PROCESSING
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLING
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PROCESSING
PROTEINS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
TECHNETIUM 99
TECHNETIUM ISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
THYROGLOBULIN
THYROID
ULTRASONOGRAPHY
USES
YEARS LIVING RADIOISOTOPES