State of spermatogenesis in rats flown aboard Kosmos-690 biosatellite. [Effects of space flight factors on. gamma. radiosensitivity of germ cells in male rats]

Journal Article · Thu Oct 26 04:00:00 EDT 1978 · Space Biol. Med. (USSR) (Engl. Transl.); (United States)

OSTI ID:6528534

Plakhuta-Plakutina, G I

In studying the modifying effects of space flight factors on radiosensitivity of various physiological systems of the body, of definite interest is the reaction of critical organs, in particular the testes, which have a high degree of heterogenic sensitivity of spermatogenic epithelium. Impairment of proliferative activity of testicular epithelium is largely related to the radiovulnerability of cells of the stem type, spermatogonia. In determining the modifying effects of weightlessness and other factors of space flights, it is necessary to compare the cytological state and quantitative evaluation of the incidence of spermatogonia, spermatocytes, spermatids, and spermatozoa in order to determine the possible injury to specific stages of spectrogenesis, depending on the radiation doses during space flights and in ground-based model experiments. The effects of radiation under weightless conditions on the reproductive glands of 30 male Wistar rats flown aboard Kosmos-690 and submitted to prolonged ..gamma.. radiation on the 10th day of the flight were investigated.

• OSTI ID: 6528534
• Journal Information: Space Biol. Med. (USSR) (Engl. Transl.); (United States), Journal Name: Space Biol. Med. (USSR) (Engl. Transl.); (United States) Vol. 12:5; ISSN SBMEA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOSATELLITES
BODY
CESIUM 137
CESIUM ISOTOPES
ELECTROMAGNETIC RADIATION
EXTERNAL IRRADIATION
GAMETES
GAMETOGENESIS
GAMMA RADIATION
GERM CELLS
GONADS
IONIZING RADIATIONS
IRRADIATION
ISOTOPES
KOSMOS SATELLITES
MALE GENITALS
MAMMALS
MORPHOLOGICAL CHANGES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RADIOSENSITIVITY
RADIOSENSITIVITY EFFECTS
RATS
RODENTS
SATELLITES
SPACE FLIGHT
SPERMATOGENESIS
SPERMATOGONIA
SPERMATOZOA
TESTES
VERTEBRATES
WHOLE-BODY IRRADIATION
YEARS LIVING RADIOISOTOPES