SPECT measurements with /sup 99m/Tc-HM-PAO in focal epilepsy

Journal Article · Thu Dec 01 00:00:00 EST 1988 · J. Cereb. Blood Flow Metab.; (United States)

DOI:https://doi.org/10.1038/jcbfm.1988.38· OSTI ID:6514766

Ryding, E; Rosen, I; Elmqvist, D; Ingvar, D H

The ability of SPECT measurements with (/sup 99m/Tc)-HM-PAO (Ceretec) to find the location of the epileptic focus was studied in patients under consideration for neurosurgical treatment for therapy-resistant focal epilepsy. The location of low (/sup 99m/Tc)-HM-PAO uptake regions found at interictal measurements, and of high (/sup 99m/Tc)-HM-PAO uptake regions found at ictal measurements, was compared to the findings of extensive ictal and interictal EEG examinations, and to the results of CT and MRT. While EEG revealed focal epileptic activity in all of the 14 patients, SPECT showed regional abnormalities in 13 (93%). CT and MRT showed abnormal findings in 30%.

• Research Organization: University Hospital, Lund (Sweden)
• OSTI ID: 6514766
• Journal Information: J. Cereb. Blood Flow Metab.; (United States), Vol. 8:6
• Country of Publication: United States
• Language: English

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