Endocrine and metabolic studies utilizing radioisotopes and labeled hormones: Annual report
This document describes research conducted from July 1960 to July 1961 on the use of radioisotopes and labeled hormones in endocrine and metabolic studies. By measuring levels of C/sup 14/-labeled proline in the femurs of rats, the author demonstrated that removal of the parathyroid glands slowed removal of calcium in bones. Preliminary studies demonstrated an inverse relationship between the level of fluorine in drinking water and the number of bone cells in the femurs of rats. The effects of x-radiation on the thyroid gland and on adjacent tissues were determined by measuring the levels of /sup 131/I in the thyroid following exposure. Enzymatically controlled processes were distinguished from physicochemical controlled process by studying the effect of /sup 131/I on the thyroid glands of frogs. Attempts to transplant parathyroid tissue onto the surface of bone were not definitive and will have to be modified. 1 fig. (TEM)
- Research Organization:
- Rice Univ., Houston, TX (USA)
- OSTI ID:
- 6500905
- Report Number(s):
- DOE/NBM-7006849; ON: DE87006849
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300 -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
AMINO ACIDS
ANIMAL CELLS
AZOLES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BONE CELLS
CARBON 14 COMPOUNDS
CARBOXYLIC ACIDS
COLLAGEN
CONNECTIVE TISSUE CELLS
DAYS LIVING RADIOISOTOPES
DRINKING WATER
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
FEMUR
FLUORIDES
FLUORINE COMPOUNDS
GLANDS
HALIDES
HALOGEN COMPOUNDS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HORMONES
HYDROGEN COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODIDES
IODINE 131
IODINE COMPOUNDS
IODINE ISOTOPES
IONIZING RADIATIONS
ISOTOPE APPLICATIONS
ISOTOPES
LABELLED COMPOUNDS
MEDICINE
METABOLISM
NEPHRECTOMY
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
OXYGEN COMPOUNDS
PARATHORMONE
PARATHYROID GLANDS
PEPTIDE HORMONES
PROLINE
PROTEINS
PYRROLES
PYRROLIDINES
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
SCLEROPROTEINS
SKELETON
SOMATIC CELLS
SURGERY
TEMPERATURE DEPENDENCE
THYROID
TRACER TECHNIQUES
WATER
X RADIATION