Effect of subclinical lead intake on calves

Journal Article · Mon Jan 01 04:00:00 EST 1973 · J. Anim. Sci.; (United States)

OSTI ID:6498390

Dinius, D A; Brinsfield, T H; Williams, E E

Sixteen bull calves were fed a 70% concentrate diet containing no added lead, 10 ppM lead from newsprint, or 10 and 100 ppM lead from lead chromate. The diets were pelleted and fed ad libitum for 100 days. Fecal and urine samples were collected and EKG and respiration rates were monitored at 25-day intervals. At the end of the 100-day feeding trial, the calves were sacrificed and samples of skeletal muscle, cerebral cortex, liver and kidney were collected for lead analysis. Supplemental lead did not affect feed consumption nor weight gain; however, newsprint depressed both intake and gain. Neither EKG patterns, heart rate nor respiration rate were affected by dietary treatment. The percentage of ingested lead excreted in feces and urine was not significantly different among treatments. There were no significant tissue accumulations of lead from feeding newsprint or 10 ppM lead chromate; however, feeding 100 ppM lead chromate resulted in accumulations of the element in liver and kidney. Samples of cerebral cortex, liver and kidney cortex were examined by electron microscopy. Changes were not detected in the cellular ultrastructure of these tissues from either control or treated animals.

• Research Organization: Dept. of Agriculture, Beltsville, MD
• OSTI ID: 6498390
• Journal Information: J. Anim. Sci.; (United States), Journal Name: J. Anim. Sci.; (United States) Vol. 37:1; ISSN JANSA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BODY
BUILDUP
CATTLE
COWS
DIGESTIVE SYSTEM
DOMESTIC ANIMALS
ELEMENTS
ENVIRONMENTAL TRANSPORT
GLANDS
KIDNEYS
LEAD
LIVER
MAMMALS
MASS TRANSFER
METALS
ORGANS
RUMINANTS
VERTEBRATES