Mutagenicity assessment of airborne particles from three polyurethane foam manufacturing facilities

Journal Article · Thu Jan 01 04:00:00 EST 1987 · Am. J. Ind. Med.; (United States)

DOI:https://doi.org/10.1002/ajim.4700110410· OSTI ID:6496479

Ong, T M; Stewart, J; Whong, W Z; Boeniger, M

In conjunction with industrial hygiene surveys, mutagenicity studies were performed for the airborne contaminants in three polyurethane manufacturing plants. Airborne particles were collected on glass-fiber filters with Hi-Vol pumps from different locations in each plant. Gases were collected in multiple-sorbent cartridges. The collected airborne particles and sorbent cartridges were extracted with organic solvents. Each extract was tested for mutagenic activity using Salmonella typhimurium TA98 and TA100. The results showed that airborne particles from all three plants are mutagenic to TA98 with or without S9 activation. The mutagenicity with S9, however, was two to four times higher than that without S9. None of the samples of gases collected on sorbent cartridges showed mutagenic activity.

• Research Organization: National Institute for Occupational Safety and Health, Morgantown, WV
• OSTI ID: 6496479
• Journal Information: Am. J. Ind. Med.; (United States), Journal Name: Am. J. Ind. Med.; (United States) Vol. 4; ISSN AJIMD
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AIR POLLUTION
BACTERIA
CHEMICAL INDUSTRY
HAZARDS
HEALTH HAZARDS
INDOOR AIR POLLUTION
INDUSTRY
MATERIALS
METABOLIC ACTIVATION
MICROORGANISMS
MUTAGEN SCREENING
MUTAGENESIS
ORGANIC COMPOUNDS
ORGANIC POLYMERS
PETROCHEMICALS
PETROLEUM PRODUCTS
PLASTICS
POLLUTION
POLYAMIDES
POLYMERS
POLYURETHANES
SALMONELLA
SALMONELLA TYPHIMURIUM
SCREENING
SYNTHETIC MATERIALS
TOXICITY