Synthesis and properties of 4-oxo-3,4-dihydrobenzo(g)pteridine-2-carboxylic acid and its derivatives

Journal Article · Sun Nov 30 23:00:00 EST 1986 · Pharmaceut. Chem. J.; (United States)

DOI:https://doi.org/10.1007/BF00766905· OSTI ID:6465609

Musatova, I S; Pol'shakov, V I; Dvoryantseva, G G; Chistyakov, V V; Elina, A S

The authors synthesize some benzo(g)pteridines containing hydroxy, N-alkyl, carboxy, or carboxamido groups in the pyrimidine moiety of the molecule. These substituents are characteristic of the drugs nalidixic and oxolinic acids and compounds of similar structure. In proving the structures of the alkyl derivatives it was important to establish the position of the alkyl radical and this question was resolved by the examination of the /sup 13/C NMR spectrum.

• Research Organization: S. Ordzhonikidze All-Union Scientific-Research Institute for Pharmaceutical Chemistry, Moscow (USSR)
• OSTI ID: 6465609
• Journal Information: Pharmaceut. Chem. J.; (United States), Journal Name: Pharmaceut. Chem. J.; (United States) Vol. 20:2; ISSN PCJOA
• Country of Publication: United States
• Language: English

Related Subjects

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59 BASIC BIOLOGICAL SCIENCES
640302 -- Atomic
Molecular & Chemical Physics-- Atomic & Molecular Properties & Theory
74 ATOMIC AND MOLECULAR PHYSICS
ANTI-INFECTIVE AGENTS
AROMATICS
AZAARENES
BIOLOGICAL EFFECTS
CARBON 13
CARBON ISOTOPES
CARBOXYLIC ACID ESTERS
CHEMICAL SHIFT
COUPLING
COUPLING CONSTANTS
DEUTERIUM COMPOUNDS
DRUGS
ESTERS
EVEN-ODD NUCLEI
HETEROCYCLIC COMPOUNDS
HYDROGEN 1
HYDROGEN COMPOUNDS
HYDROGEN ISOTOPES
INFRARED SPECTRA
INTERMEDIATE COUPLING
ISOTOPES
J-J COUPLING
LIGHT NUCLEI
LINE WIDTHS
NITRILES
NMR SPECTRA
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PHARMACOLOGY
PTERIDINES
SPECTRA
STABLE ISOTOPES
SYNTHESIS