Synthesis, purification and properties of a new class of pteridine derivatives

Conference · Tue Dec 31 23:00:00 EST 1985

OSTI ID:7190164

Ferre, J; Yim, J J; Pfleiderer, W; Jacobson, K B

A mixture of dihydroneopterin triphosphate (H/sub 2/NTP) was boiled with Tris-HCl at pH 8.5 and several compounds with unique uv and fluorescent properties were produced, one of them thought to be 6-pyruvoyl-H/sub 4/-pterin (PH/sub 4/P). This paper presents evidence that the pteridine derivatives represent a new group with unique structural characteristics and that, although none of them are PH/sub 4/P, the latter is also a precursor for their chemical synthesis. 4 refs., 2 figs.

• Research Organization: Oak Ridge National Lab., TN (USA); Valencia Univ. (Spain). Dept. of Genetics; Seoul National Univ. (Republic of Korea). Dept. of Microbiology; Konstanz Univ. (Germany, F.R.). Dept. of Chemistry
• DOE Contract Number: AC05-84OR21400
• OSTI ID: 7190164
• Report Number(s): CONF-8606150-2; ON: DE87002626
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201 -- Chemical & Physicochemical Properties
550200* -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
AROMATICS
AZAARENES
CHEMICAL PREPARATION
CHROMATOGRAPHY
DATA
EXPERIMENTAL DATA
HETEROCYCLIC COMPOUNDS
INFORMATION
LIQUID COLUMN CHROMATOGRAPHY
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PH VALUE
PTERIDINES
SEPARATION PROCESSES
SPECTRA
SYNTHESIS
ULTRAVIOLET SPECTRA