Evaluation of the potential carcinogenicity of carbon tetrachloride. Final report

Technical Report · Wed Jun 01 00:00:00 EDT 1988

OSTI ID:6428386

Carbon tetrachloride is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is Inadequate. The potency factor (F) for Carbon tetrachloride is estimated to be 59.9/(mg/kg/day), placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, carbon tetrachloride is assigned a MEDIUM hazard ranking for the purposes of RQ adjustment.

• Research Organization: Syracuse Research Corp., NY (United States)
• OSTI ID: 6428386
• Report Number(s): PB-93-185114/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
• Country of Publication: United States
• Language: English

Related Subjects

29 ENERGY PLANNING, POLICY, AND ECONOMY
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
CARBON TETRACHLORIDE
CARCINOGENS
CHLORINATED ALIPHATIC HYDROCARBONS
DATA PROCESSING
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HALOGENATED ALIPHATIC HYDROCARBONS
HUMAN POPULATIONS
NATIONAL ORGANIZATIONS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POPULATIONS
PROCESSING
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT