Evaluation of the potential carcinogenicity of dimethylcarbamoyl chlo. Final report
Technical Report
·
OSTI ID:6373653
Dimethylcarbamoyl Chloride is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is Inadequate. The potency factor (F) for dimethylcarbamoyl chloride is estimated to be 505 (mg/kg/day), placing it in potency group 1 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, dimethylcarbamoyl chloride is assigned a HIGH hazard ranking for the purposes of RQ adjustment.
- Research Organization:
- Syracuse Research Corp., NY (United States)
- OSTI ID:
- 6373653
- Report Number(s):
- PB-93-185361/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
29 ENERGY PLANNING, POLICY, AND ECONOMY
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
CARCINOGENS
CHLORIDES
CHLORINE COMPOUNDS
DATA PROCESSING
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HALIDES
HALOGEN COMPOUNDS
HUMAN POPULATIONS
NATIONAL ORGANIZATIONS
POPULATIONS
PROCESSING
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
CARCINOGENS
CHLORIDES
CHLORINE COMPOUNDS
DATA PROCESSING
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HALIDES
HALOGEN COMPOUNDS
HUMAN POPULATIONS
NATIONAL ORGANIZATIONS
POPULATIONS
PROCESSING
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT