Evaluation of the potential carcinogenicity of gamma-hexachlorocyclohexane (lindane). Final report
Gamma-Hexachlorocyclohexane (gamma-BHC or Lindane) is a probable to possible human carcinogen, classified as weight-of-evidence Group B2/C under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient to Limited, and the evidence from human studies is Inadequate. The potency factor (F) for gamma-BHC is estimated to be 7.39/(mg/kg/day), placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, gamma-BHC is assigned a MEDIUM hazard ranking for the purposes of RQ adjustment. (When the weight-of-evidence is expressed as a range, the hazard ranking is based on the higher weight-of-evidence group.)
- Research Organization:
- Syracuse Research Corp., NY (United States)
- OSTI ID:
- 6238070
- Report Number(s):
- PB-93-185064/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
- Resource Relation:
- Other Information: See also PB--86-134673 and PB--87-116679
- Country of Publication:
- United States
- Language:
- English
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