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Isoproterenol in comparison to WR-2721 as a chemoradioprotector of the rat parotid gland

Journal Article · · Invest. Radiol.; (United States)
; ;
A comparison was made of the radioprotective abilities of the chemoradioprotector WR-2721, an amino-thiol, and the beta-sympathomimetic secretogogue isoproterenol on the rat parotid gland. Using the dose-response curve of WR-2721 for gland weights as a basis for comparison, isoproterenol was found to offer significant and equal protection during both the acute (DMF, 2.5) and the chronic (DMF, 2.3) periods.
Research Organization:
Temple Univ., Philadelphia, PA
OSTI ID:
6394117
Journal Information:
Invest. Radiol.; (United States), Journal Name: Invest. Radiol.; (United States) Vol. 14:2; ISSN INVRA
Country of Publication:
United States
Language:
English

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Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BODY
COMPARATIVE EVALUATIONS
DOSE-RESPONSE RELATIONSHIPS
DRUGS
GLANDS
MAMMALS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
RADIOPROTECTIVE SUBSTANCES
RADIOSENSITIVITY EFFECTS
RATS
RODENTS
SALIVARY GLANDS
THIOLS
VERTEBRATES