Evaluation of the potential carcinogenicity of creosote. Final report
Creosote is a probable human carcinogen, classified as weight-of-evidence Group B1 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is Limited. The potency of creosote may be high, because all treated animals developed tumors in the most pertinent bioassay. In this situation, however, there is no basis for calculating a specific human potency factor (F) under the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Hence, creosote is assigned to potency group 1. Combining the weight-of-evidence group and the potency group, creosote is assigned a HIGH hazard ranking for the purposes of RQ adjustment.
- Research Organization:
- Syracuse Research Corp., NY (United States)
- OSTI ID:
- 6373829
- Report Number(s):
- PB-93-185171/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
- Resource Relation:
- Other Information: See also PB--88-179395 and PB--91-180349
- Country of Publication:
- United States
- Language:
- English
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