Evaluation of the potential carcinogenicity of dibenz(a,h)anthracene. Final report
Dibenz(a,h)anthracene is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986a). Evidence on potential carcinogenicity from animal studies is Sufficient, and the evidence from human studies is No Data. The bioassay used to calculate the potency factor suggests that dibenz(a,h)anthracene may be highly carcinogenic (i.e., all treated animals developed tumors, and therefore, there is no basis for calculating a specific human potency factor). Hence, dibenz(a,h)anthracene is assigned to potency group 1 according to the CAG's methodology for evaluating potential carcinogens (U.S. EPA, 1986b). Combining the weight-of-evidence group and the potency group, dibenz(a,h)anthracene is assigned a HIGH hazard ranking for the purposes of RQ adjustment.
- Research Organization:
- Syracuse Research Corp., NY (United States)
- OSTI ID:
- 6428281
- Report Number(s):
- PB-93-185288/XAB; CNN: EPA-68-03-3112; EPA-68-03-3182
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ANTHRACENE
AROMATICS
BIOASSAY
CALCULATION METHODS
CARCINOGENS
CONDENSED AROMATICS
DATA PROCESSING
DOCUMENT TYPES
DOSE-RESPONSE RELATIONSHIPS
HUMAN POPULATIONS
HYDROCARBONS
NATIONAL ORGANIZATIONS
ORGANIC COMPOUNDS
POPULATIONS
PROCESSING
REGULATORY GUIDES
RISK ASSESSMENT
TASK SCHEDULING
TOXICITY
US EPA
US ORGANIZATIONS
WEIGHT