Thallium-201 single-photon emission computed tomographic estimates of left ventricular mass in patients with and without ischemic heart disease

Journal Article · Wed Jul 01 04:00:00 EDT 1987 · Am. Heart J.; (United States)

DOI:https://doi.org/10.1016/0002-8703(87)90311-5· OSTI ID:6325260

Narahara, K A; Thompson, C J; Maublant, J C; Brizendine, M; Mena, I

A new automated edge detection program has been developed to estimate left ventricular mass from single-photon emission computed tomographic (SPECT) thallium-201 images of patients. Left ventricular (LV) mass was measured from contrast angiograms in 21 patients and was compared with LV mass estimated from thallium-201 tomographic studies. A comparison of angiographic mass to mass estimated from stress studies yielded an r = 0.97 (SEE = 21.6 gm) and a comparison of angiographic mass to mass determined from the redistribution images yielded r = 0.96 (SEE = 23.0 gm). Values of mass from stress and redistribution studies varied 7.3% +/- 6.7 and 8.8% +/- 9.2, respectively, when compared with values obtained by cineangiography. LV mass derived from the stress and redistribution studies were highly correlated (r = 0.97; SEE = 21.9 gm). Linear regression analysis revealed a slope of 1.06 (stress ventricular mass = 1.06 X redistribution mass - 14.9 gm). Thirteen patients had two thallium-201 SPECT studies performed approximately 1 month apart. Estimated LV mass was highly correlated when the two studies were compared (r = 0.94; SEE = 21.7 gm comparing the two stress studies; and r = 0.93, SEE = 19.4 gm for the two redistribution studies). We conclude that SPECT thallium-201 imaging can define LV mass accurately and reproducibly in normal, ischemic, or infarcted tissue.

• Research Organization: Harbor-UCLA Medical Center, Torrance
• OSTI ID: 6325260
• Journal Information: Am. Heart J.; (United States), Journal Name: Am. Heart J.; (United States) Vol. 114; ISSN AHJOA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BIOMEDICAL RADIOGRAPHY
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
HEART
HEAVY NUCLEI
ISCHEMIA
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MUSCLES
MYOCARDIUM
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
RADIOLOGY
SECONDS LIVING RADIOISOTOPES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
THALLIUM 201
THALLIUM ISOTOPES
TOMOGRAPHY
USES
VASCULAR DISEASES