The oncogenic action of ionizing radiation on rat skin

Technical Report · Mon Jan 01 00:00:00 EST 1990

DOI:https://doi.org/10.2172/6320950· OSTI ID:6320950

Burns, F J; Garte, S J

An extensive experiment involving approximately 400 rats exposed to the neon ion beam at the Bevalac in Berkeley, CA and to electrons is nearing completion. Progress is described in three areas corresponding to the specific aims of the proposal: (1) carcinogenesis and DNA strand breaks in rat skin following exposure by the neon ions or electrons; (2) oncogene activation in radiation-induced rat skin cancers; (3) DNA strand breaks in the epidermis as a function of radiation penetration. 59 refs., 4 tabs.

• Research Organization: New York Univ., NY (USA). Dept. of Environmental Medicine
• Sponsoring Organization: DOE/ER
• DOE Contract Number: FG02-87ER60539
• OSTI ID: 6320950
• Report Number(s): DOE/ER/60539-T3; ON: DE91002459; TRN: 91-000611
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
IONIZING RADIATIONS
BIOLOGICAL RADIATION EFFECTS
NEOPLASMS
RADIOINDUCTION
SKIN
ONCOGENIC TRANSFORMATIONS
BIOLOGICAL PATHWAYS
CARCINOGENESIS
DNA
DOSE-RESPONSE RELATIONSHIPS
EQUATIONS
LET
NEON IONS
ONCOGENES
PROGRESS REPORT
RADIATION PROTECTION
RATS
STRAND BREAKS
ANIMALS
BIOLOGICAL EFFECTS
BODY
CELL TRANSFORMATIONS
CHARGED PARTICLES
DISEASES
DOCUMENT TYPES
ENERGY TRANSFER
GENES
IONS
MAMMALS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PATHOGENESIS
RADIATION EFFECTS
RADIATIONS
RODENTS
VERTEBRATES
560120* - Radiation Effects on Biochemicals
Cells
& Tissue Culture
550400 - Genetics