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Title: (Oncogenic action of ionizing radiation)

Abstract

An extensive experiment involving approximately 400 rats exposed to the neon ion beam at the Bevalac in Berkeley, CA and to electrons is nearing completion. The carcinogenicity of energetic electrons was determined for comparison with the neon ion results. As in past reports we will describe progress in three areas corresponding to the specific aims of the proposal: (1) carcinogenesis and DNA strand breaks in rat skin following exposure by the neon ions or electrons; (2) DNA strand breaks in the epidermis as a function of radiation penetration; (3) oncogene activation in radiation-induced rat skin cancers. 72 refs., 6 tabs.

Publication Date:
Research Org.:
New York Univ., NY (USA). Medical Center
Sponsoring Org.:
DOE/ER
OSTI Identifier:
6067179
Report Number(s):
DOE/ER/60539-T4
ON: DE91005979; TRN: 91-002358
DOE Contract Number:
FG02-87ER60539
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 59 BASIC BIOLOGICAL SCIENCES; ELECTRONS; CARCINOGENESIS; NEON IONS; NEOPLASMS; RADIOINDUCTION; RATS; BIOLOGICAL RADIATION EFFECTS; SKIN; ONCOGENIC TRANSFORMATIONS; BIOLOGICAL PATHWAYS; DNA; DOSE-RESPONSE RELATIONSHIPS; EQUATIONS; IONIZING RADIATIONS; LET; ONCOGENES; PROGRESS REPORT; RADIATION PROTECTION; STRAND BREAKS; ANIMALS; BIOLOGICAL EFFECTS; BODY; CELL TRANSFORMATIONS; CHARGED PARTICLES; DISEASES; DOCUMENT TYPES; ELEMENTARY PARTICLES; ENERGY TRANSFER; FERMIONS; GENES; IONS; LEPTONS; MAMMALS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PATHOGENESIS; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals; 550400 - Genetics

Citation Formats

Not Available. (Oncogenic action of ionizing radiation). United States: N. p., 1990. Web. doi:10.2172/6067179.
Not Available. (Oncogenic action of ionizing radiation). United States. doi:10.2172/6067179.
Not Available. Mon . "(Oncogenic action of ionizing radiation)". United States. doi:10.2172/6067179. https://www.osti.gov/servlets/purl/6067179.
@article{osti_6067179,
title = {(Oncogenic action of ionizing radiation)},
author = {Not Available},
abstractNote = {An extensive experiment involving approximately 400 rats exposed to the neon ion beam at the Bevalac in Berkeley, CA and to electrons is nearing completion. The carcinogenicity of energetic electrons was determined for comparison with the neon ion results. As in past reports we will describe progress in three areas corresponding to the specific aims of the proposal: (1) carcinogenesis and DNA strand breaks in rat skin following exposure by the neon ions or electrons; (2) DNA strand breaks in the epidermis as a function of radiation penetration; (3) oncogene activation in radiation-induced rat skin cancers. 72 refs., 6 tabs.},
doi = {10.2172/6067179},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 1990},
month = {Mon Jan 01 00:00:00 EST 1990}
}

Technical Report:

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