Two different variants of the same tropomyosin polypeptide in clones from GM1386 human skin fibroblasts

Journal Article · Wed May 01 04:00:00 EDT 1985 · Biochem. Biophys. Res. Commun.; (United States)

DOI:https://doi.org/10.1016/0006-291X(85)91074-5· OSTI ID:6297529

Giometti, C S; Gemmell, M A; Anderson, N L

A new protein observed in two-dimensional electrophoresis patterns of proteins from the human skin fibroblast line GM1386 has been identified as a charge and molecular-weight variant of the type of tropomyosin found in smooth muscle (Tm:3). This is the second variant of Tm:3 found in GM1386 and represents a second site mutation in one of the genes coding for Tm:3. 14 references, 4 figures.

• Research Organization: Argonne National Lab., IL
• DOE Contract Number: W-31109-ENG-38
• OSTI ID: 6297529
• Journal Information: Biochem. Biophys. Res. Commun.; (United States), Journal Name: Biochem. Biophys. Res. Commun.; (United States) Vol. 128:3; ISSN BBRCA
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
59 BASIC BIOLOGICAL SCIENCES
ANIMAL CELLS
BIOLOGICAL VARIABILITY
BODY
CELL CULTURES
CLONE CELLS
CONNECTIVE TISSUE CELLS
ELECTROPHORESIS
FIBROBLASTS
GENE MUTATIONS
MOLECULAR WEIGHT
MUSCLES
MUTATIONS
ORGANIC COMPOUNDS
ORGANS
PEPTIDES
POLYPEPTIDES
PROTEINS
SKIN
SOMATIC CELLS
TROPOMYOSIN