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Components of cigarette smoke with ciliary-depressant activity

Journal Article · · New Engl. J. Med.; (United States)
Measurement of ciliary movement of soot-spore powder along exteriorized rabbit trachea during exposure to puffs of cigarette smoke or its gaseous components was studied. Cigarette smoke inhibited ciliary activity within a few puffs. Those gases which produced ciliary inhibition (50% decrease) included: formaldehyde, acrolein, HCN, NH/sub 3/, and NO/sub 2/. SO/sub 2/ also inhibited activity, but it is not present in the smoke. Gases rather than particles are responsible for inhibition.
OSTI ID:
6288660
Journal Information:
New Engl. J. Med.; (United States), Journal Name: New Engl. J. Med.; (United States) Vol. 269; ISSN NEJMA
Country of Publication:
United States
Language:
English