Sister chromatid exchanges and cell division delays induced by diethylstilbestrol, estradiol, and estriol in human lymphocytes
Journal Article
·
· Cancer Res.; (United States)
OSTI ID:6271598
It had been found previously that exposure of human lymphocytes in vitro to diethylstilbestrol (DES), a synthetic estrogen and known human carcinogen, led to the induction of sister chromatid exchangers. More sister chromatid exchanges were induced in cells from pregnant women than from men. To see if the effects of DES could be induced by other estrogens, lymphocytes from a man and a pregnant woman were treated in vitro with the natural estrogens estradiol and estriol. These did not induce sister chromatid exchanges.
- Research Organization:
- Univ. of California, Berkeley
- DOE Contract Number:
- AC03-76SF01012
- OSTI ID:
- 6271598
- Journal Information:
- Cancer Res.; (United States), Journal Name: Cancer Res.; (United States) Vol. 43; ISSN CNREA
- Country of Publication:
- United States
- Language:
- English
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