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Hydroxylation of alkanes by iodosobenzene catalyzed by tetraarylporphyrins of trivalent iron (in Russian)

Journal Article · · Bull. Acad. Sci. USSR, Div. Chem. Sci. (Engl. Transl.); (United States)
DOI:https://doi.org/10.1007/BF00954213· OSTI ID:6226409

The mechanism of activation of O/sub 2/ by cytochrome P-450, which leads to an active species oxidizing hydrocarbons, is unclear. Also unclear are the reasons for the predominant oxidation of alkanes and fatty acids at terminal methyl and methylene groups (so-called omega- and omega-1-hydroxylation). Recently systems were detected in which iron porphyrins FeP catalyze hydroxylation and epoxidation of hydrocarbons RH by iodosobenzene PhIO. With respect to the selectivity of action, the kinetic isotope effect, and stereospecificity, these systems approach an enzymic system with cytochrome P-450. In the present article, the authors report on the effect of electronic and steric factors in the structure of Fe(III) tetraarylporphyrins on the yield and selectivity of products of hydroxylation of alkanes by iodosobenzene.

Research Organization:
Institute of Chemical Physics, Chernogolovka, USSR
OSTI ID:
6226409
Journal Information:
Bull. Acad. Sci. USSR, Div. Chem. Sci. (Engl. Transl.); (United States), Journal Name: Bull. Acad. Sci. USSR, Div. Chem. Sci. (Engl. Transl.); (United States) Vol. 35:4; ISSN BACCA
Country of Publication:
United States
Language:
Russian