Long-term retention of radium in female former dial workers
The results of measurements of radium contents in 13 women made over 20 years or more were used to measure radium retention. The women were all employed at different studios of the same Illinois plant as luminous dial workers for up to 4 years. The data for each woman were fitted to an exponential function of time, yielding a biological half-life of approximately 30 to 60 years. There was a strong negative correlation between elimination rate and body content, suggesting an effect of radiation of bone resorption or remodelling. A strong negative correlation was observed between the elimination rate and the reduced x-ray score, a measure of bone damage observed radiographically in the same subjects. Age at first exposure and duration of exposure were not significantly correlated with the elimination rate. The concentration of radium in soft tissues from eight other subjects, expressed as a percentage of the terminal radium content, decreased with increasing body content, providing further evidence that radiation was affecting the elimination rate. An effect of radiation on the late retention of radium has been demonstrated. 10 references, 4 figures, 2 tables.
- Research Organization:
- Argonne National Lab., IL (USA)
- DOE Contract Number:
- W-31-109-ENG-38
- OSTI ID:
- 6195520
- Report Number(s):
- CONF-8410161-1; ON: DE85000227
- Resource Relation:
- Conference: European late effects projects conference on metals in bone, Angers, France, 11 Oct 1984
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
RADIUM 224
BIOLOGICAL HALF-LIFE
BODY BURDEN
RADIUM 226
BIOLOGICAL ACCUMULATION
EXCRETION
EXPERIMENTAL DATA
SKELETON
WOMEN
ALKALINE EARTH ISOTOPES
ALPHA DECAY RADIOISOTOPES
ANIMALS
BODY
CLEARANCE
DATA
DAYS LIVING RADIOISOTOPES
EVEN-EVEN NUCLEI
FEMALES
HEAVY NUCLEI
INFORMATION
ISOTOPES
MAMMALS
MAN
NUCLEI
NUMERICAL DATA
ORGANS
PRIMATES
RADIOISOTOPES
RADIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560161* - Radionuclide Effects
Kinetics
& Toxicology- Man